93862-56-7

Upstream product

• 938-94-3 (R,S)-2-(4'-methylphenyl) propionic acid 
• 931405-92-4 pentafluorophenyl 2-(4-methylphenyl)propionate 
• 17016-83-0 (4S)-4-isopropyl-1,3-oxazolidin-2-one 
• 264621-69-4 ethyl (S)-2-oxooxazolidinine-4-carboxylate 
• 90319-52-1 (4R)-phenyl-2-oxazolidinone 
• 93862-55-6 (S)-4-Isopropyl-3-(2-p-tolyl-acetyl)-oxazolidin-2-one 
• 74-88-4 methyl iodide 

Downstream Products

• 93922-51-1 (S)-2-(4-methylphenyl)-1-propanol 
• 93862-59-0 ethyl (R)-3-(4-methylphenyl)butanoate 
• 23430-44-6 (S)-2-(4-methylphenyl)-1-propyl p-toluenesulfonate 
• 93862-60-3 (R)-3-Oxo-6-p-tolyl-heptanoic acid methyl ester 
• 93862-58-9 1-Methyl-4-((S)-1-methyl-2-phenylsulfanyl-ethyl)-benzene 
• 93862-57-8 1-iodo-2-(4-methylphenyl)propane 
• 93862-61-4 (R)-2-Methyl-5-oxo-2-p-tolyl-cyclopentanecarboxylic acid methyl ester 
• 93862-62-5 (3S)-3-methyl-2-methylene-3-p-tolylcyclopentanone 
• 93922-52-2 (R)-3-(4-methylphenyl)butanoic acid 
• 16196-32-0 (S)-2,2,3-trimethyl-3-(p-tolyl)cyclopentan-1-one 

Relevant academic research and scientific papers

Efficient parallel resolution of pentafluorophenyl active esters using quasi-enantiomeric combinations of oxazolidin-2-ones

The parallel resolution of racemic pentafluorophenyl 2-aryl/ phenylpropanoates and butanoates using an equimolar combination of quasi-enantiomeric Evans oxazolidin-2-ones is discussed. The levels of diastereoselectivity were excellent (>90% de) leading to separable quasi-enantiomeric oxazolidin-2-ones in good yield. This methodology was used to resolve a series of structurally related 2-aryl/phenylpropanoic and butanoic acids.

Enantioselective Ring Construction: Synthesis of (+)-α-Cuparenone

Rhodium-catalyzed intramolecular C-H insertion (8->9) is shown to proceed with retention of absolute configuration.The product β-keto ester 9 is readily carried on to (+)-α-cuparenone (10).This represents a general strategy for the enantioselective formu