931995-48-1Relevant academic research and scientific papers
From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part II: Acyclic replacements for the (3S)-3-benzylpiperidine in a series of potent CCR3 antagonists
Gardner, Daniel S.,Santella III, Joseph B.,Tebben, Andrew J.,Batt, Douglas G.,Ko, Soo S.,Traeger, Sarah C.,Welch, Patricia K.,Wadman, Eric A.,Davies, Paul,Carter, Percy H.,Duncia, John V.
, p. 586 - 595 (2008/09/17)
Conformational analysis of the 3-benzylpiperidine in CCR3 antagonist clinical candidate 1 (BMS-639623) predicts that the benzylpiperidine may be replaced by acyclic, conformationally stabilized, anti-1,2-disubstituted phenethyl- and phenpropylamines. Ab i
