932-15-0Relevant articles and documents
Industrial production method of 4-amino-5-imidazolecarboxamide
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Paragraph 0040; 0045-0048; 0049; 0054, (2020/07/15)
The invention discloses an industrial production method of 4-amino-5-imidazolecarboxamide, belonging to the technical field of organic synthesis. The industrial production method comprises the following steps: S1, reacting diaminomaleonitrile with formamide under the action of phosphorus oxychloride to generate an intermediate 1; and S2, subjecting the intermediate 1 to a ring closing reaction under an alkaline condition so as to generate 4-amino-5-imidazolecarboxamide. The method has the advantages of simple raw materials, low price, short reaction steps, short production period, simple operation and easy realization of industrial production, avoids the generation of cyano-containing wastewater, nitrogen-containing wastewater and the like in traditional synthesis methods, causes very small environmental protection pressure, and realizes preparation of the high-quality 4-amino-5-imidazolecarboxamide only through two reactions.
