932-23-0

Basic information

• Product Name: 2-Chloro-3-hydroxycyclohex-2-en-1-one, 98%
• Synonyms: 2-Chloro-1,3-cyclohexanedione
• CAS NO: 932-23-0
• Molecular Formula: C₆H₇ClO₂
• Molecular Weight: 146.57
• Mol File: 932-23-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Chloro-3-hydroxycyclohex-2-en-1-one, 98%(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-3-hydroxycyclohex-2-en-1-one, 98%(932-23-0)
• EPA Substance Registry System: 2-Chloro-3-hydroxycyclohex-2-en-1-one, 98%(932-23-0)

Safety Data

• Hazardous Substances Data: 932-23-0(Hazardous Substances Data)

Upstream product

• 1460-08-8 2-diazocyclohexane-1,3-dione 
• 75-62-7 Bromotrichloromethane 
• 6838-66-0 1,2-bis((trimethylsilyl)oxy)cyclopent-1-ene 
• 17530-74-4 2,2-Dichloro-1,3-cyclohexanedione 
• 504-02-9 1,3-cylohexanedione 

Downstream Products

• 17583-14-1 methyl-2 oxo-7 tetrahydro-4,5,6,7 benzothiazole 
• 146032-25-9 2-Oxoadipinsaeure-6-methylester-1-N¹-phenylamidrazon 
• 170699-80-6 C₁₃H₁₆ClN₃O₃ 
• 170699-82-8 C₁₄H₁₈ClN₃O₃ 

Relevant articles and documents

Copper Triflate Mediated α-Monohalogenation of α-Diazo β-Ketosulfones with Ammonium Halides

Copper triflate mediated α-monohalogenation of α-diazo β-ketosulfones with ammonium halides provides the corresponding α-halo β-ketosulfones. Different metal triflates are investigated for this facile and efficient transformation. A plausible mechanism is proposed.

SAR studies of 3-cyclopropanecarbonyloxy-2-cyclohexen-1-one as inhibitors of 4-hydroxyphenylpyruvate dioxygenase

Various 3-cyclopropanecarbonyloxy-2-cyclohexen-1-one 1 derivatives have been synthesized and tested as inhibitors of 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) from pig liver. The inhibition results indicated that well-positioned dicarbonyl groups as well as the cyclopropyl group of 1 were essential for potent inhibition. Substitution at the 2-position of the ring system has a significant effect on inhibitor potency, while the 5-position can undergo substantial variations and retain inhibitor potency. In the compounds examined, 2-chloro substituted 12 is the best inhibitor of all with IC50 of 15 nM, the rest of the synthesized analogues were less potent inhibitors than the parent compound.