93228-48-9Relevant articles and documents
Carboxylation of N-H/C-H bonds using n-heterocyclic carbene copper(I) complexes
Boogaerts, Ine I. F.,Fortman, George C.,Furst, Marc R. L.,Cazin, Catherine S. J.,Nolan, Steven P.
supporting information; experimental part, p. 8674 - 8677 (2011/01/06)
Greenhouse gas makes good: A simple copper-mediated protocol has been developed where N-H or C-H bonds can be directly functionalized using an easily prepared catalyst. The novel [1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene] copper(I) hydroxide, [Cu(IPr)(OH)], permits the facile activation and carboxylation of N-H and C-H bonds with pKavalues of less than 27.7 (see scheme).