93244-96-3Relevant academic research and scientific papers
Copper-Mediated Vicarious Substitution of 1,3-Dinitrobenzene with Iodophenols or Iodomethyl Phenyl Sulfoxide/Sulfone
Haglund, Olof,Hai, Abdul A. K. M.,Nilsson, Martin
, p. 942 - 944 (2007/10/02)
1,3-Dinitrobenzene reacts with 4-iodophenol or 2-iodophenol in the presence of copper(I) tert-butoxide and pyridine to give 2',6'-dinitrobiphenyl-4-ol and 1-nitrodibenzofuran, respectively, in good yield.Similarly, iodomethyl phenyl sulfone or sulfoxide a
SPECIFIC ORTHO ORIENTATION IN THE VICARIOUS SUBSTITUTION OF HYDROGEN IN AROMATIC NITRO COMPOUNDS WITH CARBANION OF CHLOROMETHYL PHENYL SULFONE
Makosza, M.,Glinka, T.,Kinowski, A.
, p. 1863 - 1868 (2007/10/02)
Vicarious nucleophilic substitution of hydrogen atoms in nitroarenes with chloromethylphenyl sulfone proceeds selectively ortho to the nitro group when carried out in t-BuOK/THF base/solvent system.In the majority of 3-substituted nitrobenzene derivatives substitution occurs at the most hindered position 2.These conditions offer an efficient method of synthesis of 2,6 and 2,3-disubstituted nitrobenzene derivatives.
