93249-44-6

Basic information

• Product Name: 2-Fluoro-5-methylbenzaldehyde
• Synonyms: 2-FLUORO-5-METHYLBENZALDEHYDE;Benzaldehyde, 2-fluoro-5-methyl- (9CI);2-Fluoro-5-methylbenzaidehyde;4-Fluoro-3-formyltoluene;4-Fluoro-3-formyltoluene, 6-Fluoro-m-tolualdehyde;Benzaldehyde, 2-fluoro-5-methyl-;2-fluoro-5-methyl- (9CI)2-Fluoro-5-methylbenzaidehyde;Fluoro-5-methylbenzaldehyde
• CAS NO: 93249-44-6
• Molecular Formula: C₈H₇FO
• Molecular Weight: 138.14
• Product Categories: Fluorin-contained benzaldehyde series;ALDEHYDE;Aromatic Aldehydes & Derivatives (substituted);Benzaldehyde
• Mol File: 93249-44-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 89 °C15 mm Hg(lit.)
• Flash Point: 178 °F
• Appearance: Light yellow or a colourless liquid
• Density: 1.129 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.364mmHg at 25°C
• Refractive Index: n20/D 1.5160(lit.)
• Storage Temp.: Room temperature.
• Sensitive: Air Sensitive
• CAS DataBase Reference: 2-Fluoro-5-methylbenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-5-methylbenzaldehyde(93249-44-6)
• EPA Substance Registry System: 2-Fluoro-5-methylbenzaldehyde(93249-44-6)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-27-36/37/39-45
• RIDADR: UN 3265 8/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 93249-44-6(Hazardous Substances Data)

Usage

General Description

2-Fluoro-5-methylbenzaldehyde is an organic compound with the chemical formula C8H7FO. It is a pale yellow liquid with a strong, sweet aroma commonly used as a flavoring agent. This chemical is often used in the production of pharmaceuticals, pesticides, and dyes due to its aromatic properties. It is also known for its use as a precursor in the synthesis of various organic compounds. Additionally, 2-Fluoro-5-methylbenzaldehyde has applications in the fragrance industry, where it is used for its unique scent. However, it is important to handle this chemical with care, as it can be harmful if it comes into contact with the skin or eyes, and it should be stored in a cool, dry place away from direct sunlight.

InChI:InChI=1/C8H7FO/c1-6-2-3-8(9)7(4-6)5-10/h2-5H,1H3

Upstream product

• 352-32-9 p-fluorotoluene 
• 4885-02-3 Dichloromethyl methyl ether 

Downstream Products

• 851753-68-9 4-(2-formyl-4-methyl-phenyl)-piperazine-1-carboxylic acid tert-butyl ester 
• 934691-75-5 5-methyl-2-(phenoxy)benzaldehyde 
• 1182350-28-2 [3-(2-formyl-4-methyl-phenoxy)-phenyl]-acetic acid ethyl ester 
• 1213237-53-6 2,2,2-trifluoro-N-(6-(2-fluoro-5-methylbenzoyl)imidazo[1,2-a]pyridin-2-yl)acetamide 
• 1227682-28-1 C₂₆H₂₀ClFN₆O₃ 
• 771566-62-2 C₁₁H₇FN₂ 
• 208718-14-3 S 23757 
• 952568-49-9 (R)-tert-butyl 3-benzyl-4-(3-(2-(2-formyl-4-methylphenoxy)-5-methylphenyl)propanoyl)piperazine-1-carboxylate 
• 1191415-61-8 S-(2-formyl-4-methylphenyl) ethanethioate 
• 699016-43-8 tert-butyl [(2R)-2-(3-chlorophenyl)-2-hydroxyethyl][(1R)-2-[4-[(2-formyl-4-methylphenyl)thio]-phenyl]-1-methylethyl]carbamate 

Relevant articles and documents

Direct formylation of fluorine-containing aromatics with dichloromethyl alkyl ethers

Formylations of fluorine-containing aromatic compounds with dichloromethyl alkyl ethers have been investigated. Dichloromethyl propyl ether and dichloromethyl butyl ether have been applied for the formylation of fluorine-containing anisoles to give the corresponding aldehydes in good yields. Application of these ethers is preferable to that of methyl ether, which is prepared from volatile methyl formate. Reaction of fluorine-containing phenols with these dichloromethyl alkyl ethers did not give salicylaldehyde derivatives, leading instead to corresponding aryl formates in high yields. A plausible mechanism is discussed.