93259-25-7Relevant academic research and scientific papers
Enolate-mediated 1,3-dipolar cycloaddition reaction of β-functionalized ketones with nitrile oxides: Direct access to 3,4,5-trisubstituted isoxazoles
Zhou, Xiao,Xu, Xianhong,Shi, Zhenyan,Liu, Kun,Gao, Hua,Li, Wenjun
supporting information, p. 5246 - 5250 (2016/07/06)
TMG-catalyzed [3 + 2] organocatalytic 1,3-dipolar cycloaddition reactions of β-functionalized ketones with nitrile oxides have been developed. This strategy could generate 3,4,5-trisubstituted isoxazoles in high yields and regioselectivities.
Synthesis method of 3,4,5-trisubstituted isoxazole type compound
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Paragraph 0018, (2016/10/09)
The invention discloses a synthesis method of a 3,4,5-trisubstituted isoxazole type compound. In reaction solvent, the 3,4,5-trisubstituted isoxazole type compound is obtained through reaction with substituted acetoacetamide and chloro-substituted aldoxim
