932699-75-7Relevant academic research and scientific papers
A spirodiepoxide-based strategy to the A-B ring system of pectenotoxin 4
Lotesta, Stephen D.,Hou, Yongquan,Williams, Lawrence J.
, p. 869 - 872 (2007/10/03)
(Chemical Equation Presented) A synthesis of a pectenotoxin 4 C1-C15 segment is reported. Suitable C1-C7 and C8-C15 segments were prepared, coupled, converted to I and the C3-hydroxy variant, and then cyclized. Key findings include the stereoselective conversion of the allene to the corresponding spirodiepoxide, oxidative cleavage of the p-methoxybenzyl ether, and cyclization of the spirodiepoxide to spiroketal II.
