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2-Cyclopentylacetamide is a chemical compound with the molecular formula C7H13NO. It is a white crystalline solid that is soluble in water and various organic solvents. 2-CYCLOPENTYLACETAMIDE is primarily used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, particularly in the production of certain antibiotics and antifungal agents. Its structure consists of a cyclopentyl group attached to an acetamide moiety, which contributes to its unique chemical properties and reactivity. Due to its potential applications in the development of new drugs and its role in chemical research, 2-cyclopentylacetamide is an important compound in the field of organic chemistry.

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  • 933-04-0 Structure
  • Basic information

    1. Product Name: 2-CYCLOPENTYLACETAMIDE
    2. Synonyms: 2-CYCLOPENTYLACETAMIDE
    3. CAS NO:933-04-0
    4. Molecular Formula: C7H13NO
    5. Molecular Weight: 127.19
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 933-04-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-CYCLOPENTYLACETAMIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-CYCLOPENTYLACETAMIDE(933-04-0)
    11. EPA Substance Registry System: 2-CYCLOPENTYLACETAMIDE(933-04-0)
  • Safety Data

    1. Hazard Codes: Xn
    2. Statements: 22
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 933-04-0(Hazardous Substances Data)

933-04-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 933-04-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 9,3 and 3 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 933-04:
(5*9)+(4*3)+(3*3)+(2*0)+(1*4)=70
70 % 10 = 0
So 933-04-0 is a valid CAS Registry Number.

933-04-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Cyclopentylacetamide

1.2 Other means of identification

Product number -
Other names Cyclopentyl-essigsaeure-amid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:933-04-0 SDS

933-04-0Relevant articles and documents

Photoinduced remote regioselective radical alkynylation of unactivated C-H bonds

Hu, Qu-Ping,Liu, Yong-Ze,Liu, Yu-Tao,Pan, Fei

, p. 2295 - 2298 (2022/02/25)

A method for the remote regioselective alkynylation of unactivated C(sp3)-H bonds in diverse aliphatic amides by photogenerated amidyl radicals has been developed. The site-selectivity is dominated via a 1,5-hydrogen atom transfer (HAT) process of the amide. Mild reaction conditions and high regioselectivity are demonstrated in this methodology.

Remote Regioselective Radical C-H Functionalization of Unactivated C-H Bonds in Amides: The Synthesis of gem-Difluoroalkenes

Hu, Qu-Ping,Cheng, Jing,Wang, Ying,Shi, Jie,Wang, Bi-Qin,Hu, Ping,Zhao, Ke-Qing,Pan, Fei

, p. 4457 - 4462 (2021/05/26)

The site-selective functionalization of unactivated aliphatic amines is an attractive and challenging synthetic approach. We herein report a general strategy for the remote site-selective functionalization of unactivated C(sp3)-H bonds in amides by photogenerated amidyl radicals to form gem-difluoroalkenes with trifluoromethyl-substituted alkenes. The site selectivity is controlled by a 1,5-hydrogen atom transfer (HAT) process of the amide. This photocatalyzed transformation shows both chemo- and site-selectivity, facilitating the formation of a secondary, tertiary, or quaternary carbon center.

SMALL MOLECULE VE-PTP INHIBITORS

-

, (2022/01/05)

The present disclosure relates to compounds capable of inhibiting vascular endothelial protein tyrosine phosphatase (VE-PTP). These compounds are also capable of activating Tie2 receptor-mediated signaling. The present disclosure also relates to pharmaceutically acceptable salts of said compounds, to pharmaceutical compositions comprising such compounds and/or pharmaceutically acceptable salts thereof, and to the use of such compounds, pharmaceutically acceptable salts thereof, and/or pharmaceutical compositions comprising the same in treating diseases and/or conditions mediated by VE-PTP signaling, such as those mediated by Angiopoietm/Tie2 signaling.

Remote Directed Isocyanation of Unactivated C(sp3)-H Bonds: Forging Seven-Membered Cyclic Ureas Enabled by Copper Catalysis

Zhang, Hongwei,Tian, Peiyuan,Ma, Lishuang,Zhou, Yulu,Jiang, Cuiyu,Lin, Xufeng,Xiao, Xiao

, p. 997 - 1002 (2020/02/15)

Reported herein is an unprecedented copper-catalyzed site-selective ?-C(sp3)-H bonds activation of aliphatic sulfonamides for constructing the synthetically useful seven-membered N-heterocycles. A key to success is the use of in-situ-formed amide radicals, to activate the inert C(sp3)-H bond, and inexpensive TMSNCO, as a coupling reagent under mild conditions. To the best of our knowledge, this represents the first use of alkylamine derivatives as a five-membered synthon to prepare a seven-membered N-heterocycles.

Efficient synthesis of unsymmetrical sulfamides from sulfamic acid salts by activation with triphenylphosphine ditriflate

Shehata, Mina F.,Short, Melanie A.,Sanders, Matthew A.,Roizen, Jennifer L.

supporting information, p. 3186 - 3194 (2019/03/13)

A general approach to prepare unsymmetrical sulfamides is described. This method relies on the activation of sulfamic acid salts with triphenylphosphine ditriflate, and subsequent trapping by a nucleophilic amine. This strategy improves access to N-octade

5-(PYRIDIN-3-YL)OXAZOLE ALLOSTERIC MODULATORS OF M4 MUSCARINIC ACETYLCHOLINE RECEPTOR

-

Page/Page column 72, (2019/01/16)

Provided are 5-(pyridin-3-yl) oxazole compounds, the compositions comprising these compounds and the uses of these compositions in the potential prevention or treatment of such diseases in which M4 muscarinic acetylcholine receptors are involved.

Copper-Catalyzed Amide Radical-Directed Cyanation of Unactivated Csp3-H Bonds

Zhang, Hongwei,Zhou, Yulu,Tian, Peiyuan,Jiang, Cuiyu

, (2019/03/19)

A method for site-selective intermolecular δ/?-Csp3-H cyanation of aliphatic sulfonamides is developed using TsCN as the cyanating reagent, catalyzed by a Cu(I)/phenanthroline complex. The mild, expeditious, and modular protocol allows efficient remote Csp3-H cyanation with good functional group tolerance and high regioselectivity. Mechanistic studies indicate that the reaction might proceed through a Cu(I)-mediated N-F bond cleavage to generate an amidyl radical, 1,5-HAT, and cyano group transfer of the resulting carbon radical with TsCN.

Corresponding amine nitrile and method of manufacturing thereof

-

Paragraph 0138; 0139; 0140; 0149; 0150, (2018/05/07)

The invention relates to a manufacturing method of nitrile. Compared with the prior art, the manufacturing method has the characteristics of significantly reduced using amount of an ammonia source, low environmental pressure, low energy consumption, low production cost, high purity and yield of a nitrile product and the like, and nitrile with a more complex structure can be obtained. The invention also relates to a method for manufacturing corresponding amine from nitrile.

SUBSTITUTED PYRROLIDINE AND PIPERIDINE COMPOUNDS, DERIVATIVES THEREOF, AND METHODS FOR TREATING PAIN

-

Page/Page column 78-79, (2009/10/22)

The present application relates to pyrrolidine, piperidine, and other nitrogen-containing heterocyclic derivatives and the use of these compounds for treating and preventing pam or inflammation. The analgesic compounds demonstrate efficacy in the treatment of neuropathic pain resulting from a variety of conditions such as diabetic neuropathy, HIV infections, and post-herpetic neuralgia.

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