93305-56-7

Basic information

• Product Name: 5-(hydroxy(phenyl)methyl)-4-methylfuran-2(5H)-one
• CAS NO: 93305-56-7
• Molecular Weight: 204.225
• Mol File: 93305-56-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(hydroxy(phenyl)methyl)-4-methylfuran-2(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(hydroxy(phenyl)methyl)-4-methylfuran-2(5H)-one(93305-56-7)
• EPA Substance Registry System: 5-(hydroxy(phenyl)methyl)-4-methylfuran-2(5H)-one(93305-56-7)

Safety Data

• Hazardous Substances Data: 93305-56-7(Hazardous Substances Data)

Upstream product

• 6124-79-4 4-methyl-2(5H)-furanone 
• 100-52-7 benzaldehyde 

Relevant articles and documents

Chiral quaternary ammonium aryloxide/N,O-bis(trimethyl-silyl)acetamide combination as efficient organocatalytic system for the direct vinylogous aldol reaction of (5H)-furan-2-one derivatives

A chiral quaternary ammonium amide was generated in situ from N,O-bis(trimethylsilyl)acetamide (BSA) as non-nucleophilic Bronsted base precursor and the combination of chiral quaternary ammonium halide/sodium aryloxide as chiral Lewis base. This system was applied to an anti-selective organocatalytic direct vinylogous aldol (ODVA) reaction of (5H)-furan-2-one derivatives with aldehydes. Several 5-(1′-hydroxy)-γ-butenolides were obtained in good diastereomeric ratios (up to 95/5) and excellent enantioselectivities (up to 94%) with both aliphatic or (hetero)aromatic aldehydes, so providing a rare example of general and efficient conditions for the ODVA reaction. Copyright