933063-85-5Relevant academic research and scientific papers
2′-O-hydroxyalkoxymethylribonucleosides and their incorporation into oligoribonucleotides
Mikhailov, Sergey N.,Bobkov, Georgii V.,Brilliantov, Kyrill V.,Rozenski, Jef,Van Aerschot, Arthur,Herdewijn, Piet,Fisher, Michael H.,Juliano, Rudolph L.
, p. 1509 - 1512 (2008/09/18)
A simple and efficient method for the preparation of pyrimidine 2′-O-hydroxyethoxymethylribonucleosides and 2′-O- hydroxypropoxymethylribonucleosides has been developed. These modified nucleosides were incorporated into oligoribonucleotides, which were sh
Synthesis of oligoribonucleotides containing pyrimidine 2′-O-[(hydroxyalkoxy)methyl]ribonucleosides
Bobkov, Georgii V.,Brilliantov, Kirill V.,Mikhailov, Sergey N.,Rozenski, Jef,Van Aerschot, Arthur,Herdewijn, Piet
, p. 804 - 819 (2008/02/02)
A simple and efficient method for the preparation of pyrimidine 2′-O-[(2-hydroxyethoxy)methyl]ribonucleosides and 2′-O-[(3- hydroxypropoxy)methyl]ribonucleosides has been developed. These modified nucleosides were incorporated into oligoribonucleotides, which were shown to form stable RNA/RNA duplexes.
