93308-49-7Relevant academic research and scientific papers
UREA BASED LIPOXYGENASE INHIBITING COMPOUNDS
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, (2008/06/13)
Substituted phenyl, naphthyl, and thienyl N-hydroxy urea compounds form a class of potent inhibitors of 5-and 12-lipoxygenase and are thus useful compounds in the treatment of inflammatory disease states where leukotrienes and other products of lipoxygenase enzyme activity are implicated.
Structure-activity analysis of a class of orally active hydroxamic acid inhibitors of leukotriene biosynthesis
Summers,Gunn,Martin,Martin,Mazdiyasni,Stewart,Young,Bouska,Dyer,Brooks,Carter
, p. 1960 - 1964 (2007/10/02)
The nature of the carbonyl and nitrogen substituents of hydroxamic acids has a major influence on the biological profile of these compounds. Hydroxamates with small groups such as methyl appended to the carbonyl and relatively large nitrogen substituents
