93315-29-8Relevant academic research and scientific papers
Inhalation by design: Novel tertiary amine muscarinic M3 receptor antagonists with slow off-rate binding kinetics for inhaled once-daily treatment of chronic obstructive pulmonary disease
Glossop, Paul A.,Watson, Christine A. L.,Price, David A.,Bunnage, Mark E.,Middleton, Donald S.,Wood, Anthony,James, Kim,Roberts, Dannielle,Strang, Ross S.,Yeadon, Michael,Perros-Huguet, Christelle,Clarke, Nicholas P.,Trevethick, Michael A.,MacHin, Ian,Stuart, Emilio F.,Evans, Steven M.,Harrison, Anthony C.,Fairman, David A.,Agoram, Balaji,Burrows, Jane L.,Feeder, Neil,Fulton, Craig K.,Dillon, Barry R.,Entwistle, David A.,Spence, Fiona J.
supporting information; experimental part, p. 6888 - 6904 (2011/12/03)
A novel tertiary amine series of potent muscarinic M3 receptor antagonists are described that exhibit potential as inhaled long-acting bronchodilators for the treatment of chronic obstructive pulmonary disease. Geminal dimethyl functionality pr
