93318-88-8

Basic information

• Product Name: Benzenemethanol, a-ethynyl-4-methyl-a-(4-methylphenyl)-
• Synonyms: 1,1-ditolyl-2-propyn-1-ol;1,1-di(p-tolyl)prop-2-in-1-ol;ditolylethynylmethanol;bis(4-methylphenyl)-2-propyn-1-ol;1,1-bis(4-methylphenyl)prop-2-yn-1-ol;1,1-Di-p-tolyl-prop-2-yn-1-ol;1,1-di-p-tolyl-2-propyn-1-ol
• CAS NO: 93318-88-8
• Molecular Formula: C17H16O
• Molecular Weight: 236.313
• Mol File: 93318-88-8.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, a-ethynyl-4-methyl-a-(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, a-ethynyl-4-methyl-a-(4-methylphenyl)-(93318-88-8)
• EPA Substance Registry System: Benzenemethanol, a-ethynyl-4-methyl-a-(4-methylphenyl)-(93318-88-8)

Safety Data

• Hazardous Substances Data: 93318-88-8(Hazardous Substances Data)

Usage

General Description

Benzenemethanol, a-ethynyl-4-methyl-a-(4-methylphenyl)- is a chemical compound with a complex and specific structure, with both aromatic and aliphatic groups. Its chemical formula is C16H14O, and it is commonly used in organic synthesis and pharmaceutical research. Its structure contains a benzene ring with a hydroxyl group attached, as well as an alkyne and a methyl group. Benzenemethanol, a-ethynyl-4-methyl-a-(4-methylphenyl)- is important in the development of various drugs and organic materials due to its unique structure and reactivity. While it has potential for valuable applications, its reactivity and potential hazards require careful handling and consideration in laboratory settings.

Upstream product

• 611-97-2 bis(p-methylphenyl)-methanone 
• 74-86-2 acetylene 
• 1066-26-8 sodium acetylide 
• 874-60-2 4-methyl-benzoyl chloride 
• 328918-13-4 C₂₀H₂₄OSi 
• 75-20-7 calcium carbide 
• 4301-14-8 acetylenemagnesium bromide 

Downstream Products

• 350821-23-7 1,2,4,5-Tetrakis-(1-chloro-3,3-di-p-tolyl-propa-1,2-dienyl)-3,6-dimethyl-benzene 
• 109472-19-7 4-hydroxy-1,1-di-p-tolyl-pent-1-en-3-one 
• 1311196-90-3 4-(di-p-tolylmethylene)-5-phenyl-1-(phenylsulphonyl)-4,5-dihydro-1H-pyrazole 
• 1311197-42-8 N-(2-cyano-1-phenyl-3,3-di-p-tolylallyl)benzenesulfonamide 
• 350821-27-1 tetrakis(3-hydroxy-3,3-di-p-tolyl-1-propynyl)-p-xylene 
• 96673-62-0 1,1,6,6-tetrakis(4-methylphenyl)-2,4-hexadiyne-1,6-diol 
• 102171-61-9 1,1-di-p-tolyl-pent-2-yne-1,4-diol 
• 768295-67-6 1,1-di-p-tolylpropan-1-ol 

Relevant articles and documents

Development of Axially Chiral Styrene-Type Carboxylic Acid Ligands via Palladium-Catalyzed Asymmetric C-H Alkynylation

A weakly coordinated carboxylate-directed palladium-catalyzed atroposelective C-H alkynylation method for the development of novel axially chiral styrene-type carboxylic acids is disclosed. This transformation exhibits good yields (up to 85%), excellent enantiocontrol (up to 99% ee), and mild conditions. Notably, the synthetic utility of the resulting alkynyl carboxylic acid derivatives was demonstrated by various derivatizations as well as their potential as chiral ligands in asymmetric C-H activations.

Visible Light Induced Cyclization to Spirobi[indene] Skeletons from Functionalized Alkylidienecyclopropanes

In this paper, we revealed a metal-free and visible light photoinduced method for the rapid construction of spirobi[indene] skeletons, providing a simple and efficient way for easy access to spirobi[indene] scaffolds under mild conditions along with a broad substrate scope and good functional group tolerance.

Pd(II)-Catalyzed Enantioselective Alkynylation of Unbiased Methylene C(sp3)-H Bonds Using 3,3′-Fluorinated-BINOL as a Chiral Ligand

The first Pd(II)-catalyzed enantioselective alkynylation of unbiased methylene β-C(sp3)-H bonds is reported. The readily accessible and tunable BINOL derivatives are used as chiral ligands in C-H activation for the first time. 3,3′-Fluorinated-