93327-76-5

Upstream product

• 100954-03-8 phenyl 3-phenylprop-2-ynoate 
• 17292-61-4 2,3-butanedione mono-(O-acetyl oxime) 
• 17292-56-7 butane-2,3-dione-mono-(O-benzoyl oxime ) 
• 24561-40-8 C₁₂H₁₃NO₄ 
• 24578-08-3 C₁₁H₁₀N₂O₅ 
• 90-02-8 salicylaldehyde 
• 40473-50-5 2-(hydroxy(phenyl)methyl)phenol 
• 117-99-7 2-Hydroxybenzophenone 
• 141-97-9 ethyl acetoacetate 
• 1694-31-1 tert-butyl acetoacetate 
• 108-86-1 bromobenzene 

Relevant academic research and scientific papers

The visible-light-induced acylation/cyclization of alkynoates with acyl oximes for the construction of 3-acylcoumarins

A nitrogen-centered radical-mediated carbon-carbon bond cleavage strategy is described to synthesize functionalized 3-acylcoumarins. The strategy is enabled by the visible-light-induced acylation/cyclization of alkynoates with various acyl oxime compounds in acetonitrile. The difunctionalization of carbon-carbon triple bonds precedes the generation of iminyl radicals, which is followed by the formation of acyl radicals. The acyl radicals then attack the carbon-carbon triple bonds, followed by 5-exo-trigcyclization and 1,2-ester migration. This strategy has wide substrate adaptability and good substituent tolerance.

One-pot synthesis of 3,4-disubstituted coumarins under catalysis of Mn 3O4 nanoparticles

The one-pot synthesis of 3,4-disubstituted coumarins from substituted 2-(hydroxymethyl)phenols with β-keto esters catalyzed by Mn 3O4 nanoparticles was developed. A series of 3,4-disubstituted coumarin derivatives were obtained in good yields. A new method for the one-pot synthesis of 3,4-disubstituted coumarins from substituted 2-(hydroxymethyl)phenols with β-keto esters catalyzed by Mn 3O4 nanoparticles has been developed. A series of 3,4-disubstituted coumarin derivatives were synthesized from substituted 2-(hydroxymethyl)phenols and β-keto esters in good yields. Copyright