93328-36-0

Upstream product

• 605-02-7 1-phenylnaphthalene 
• 94574-45-5 4-phenyl-1-naphthoic acid 
• 59951-65-4 1-bromo-4-phenylnaphthalene 
• 93321-17-6 1-hydroxymethyl-4-phenylnaphthalene 

Downstream Products

• 13280-69-8 1-methyl-4-phenylnaphthalene 

Relevant academic research and scientific papers

Synthesis of 1-Aryltetralins and 1-Arylnaphthalenes via (4 + 2) Annulation of β-Ketosulfones with Styryl Bromides

A novel route has been developed for the synthesis of various substituted 1-aryltetralins 6 and 1-arylnaphthalenes 8 via (1) K2CO3-mediated α-styrylation of β-ketosulfones 3 with bromostyryl bromides 4 and (2) stereocontrolled NaBH4-promoted reduction of the resulting γ-alkenones 5, followed by BF3·OEt2-catalyzed intramolecular annulation of the corresponding γ-alkenols 7 under rt/5 h and reflux/10 h conditions, respectively. The key structures of 6 and 8 were confirmed by X-ray crystallographic analysis. A plausible mechanism has been proposed.