933477-84-0

Usage

Molecular structure

A complex ester derivative of piperidinecarboxylic acid with a hydroxy and methylamino group.

Optical activity

The compound is optically active with a configuration of (3R,4R)-rel-.

Ester group

The 1,1-dimethylethyl ester group adds to the compound's properties and potential applications.

Scientific and industrial applications

The compound is used in various scientific and industrial applications, including pharmaceutical research and drug development.

Importance in organic chemistry

Its specific properties and potential applications make it an important compound in the field of organic chemistry.

Upstream product

• 161157-50-2 tert-butyl 7-oxa-3-azabicyclo[4.1.0]heptane-3-carboxylate 
• 74-89-5 methylamine 
• 593-51-1 methylamine hydrochloride 

Relevant academic research and scientific papers

Ring-opening addition reactions of 1-tert-Butoxycarbonyl-3,4- epoxypiperidine with Amine Nucleophiles

Ring-opening addition reactions of 1-tert-butoxycarbonyl-3,4- epoxypiperidine leading to the formation of the corresponding regioisomeric trans-β -aminoalcohols were carried out with three different types of amine nucleophiles under different reaction conditions with a view to study the reactivity and regioselectivity.

MUTILIN DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME

The invention is intended to provide a novel compound which is useful as an antibacterial agent and a manufacturing intermediate thereof and relates to a mutilin derivative represented by the formula (I) which is useful as an antibacterial agent against a multidrug resistant organism, a manufacturing intermediate thereof and the like. In the formula (I), R1 represents an ethyl group or a vinyl group, P1 represent H or a protecting group for a hydroxy group, R2 and R3 represent H or the like, G represents CH2 or the like, A represents -S-, -SO2-, -O- or the like, m represents an integer of 0 to 4, the Q1 ring represents a saturated heterocyclic group, R4 represents H, a lower alkyl group or the like, and W represents a group represented by the formula (W-1) or an amino protection group. In the formula (W-1), X represents a lower alkylene chain, a single bond or the like, Z1 represents CH or the like, Z2, Z3 and Z4 represent N or the like, and Y1 and Y2 represent H, an amino group, a group represented by the formula (Y-1) or the like. In the formula (Y-1), the Q2 ring represents a saturated heterocyclic group, and R9 and R10 represents H, a lower alkyl group or the like. (I) (W-1) (Y-1)