93355-73-8Relevant academic research and scientific papers
New approaches for the synthesis of 1,3,4-thiadiazole and 1,2,4-triazole derivatives with antimicrobial activity
Wardakhan, Wagnat W.,El-Sayed, Nahed N. E.
experimental part, p. 790 - 804 (2009/10/15)
The thiosemicarbazide derivatives 3a and 3b were cyclized in the presence of concentrated sulfuric acid to give the 5-cyanomethyl-1,3,4-thiadiazole derivatives 4a and 4b, respectively. The latter products were used for many heterocyclic transformations to
Hydrazones in heterocyclic synthesis; synthesis of 1,3,4-thiadiazole derivatives
Erian, Ayman Wahba,Manhi, Fatma Mohamed,Zayed, Salem El-Gohary,Ali, Fatma Ahmed,Elnagdi, Mohamed Hilmy
, p. 127 - 139 (2007/10/03)
A new synthesis of 1,3,4-thiadiazoles has been achieved. The reactivity of certain alkylheterocycles towards electrophilic reagents are reported.
STUDIES WITH POLYFUNCTIONALLY SUBSTITUTED HETEROAROMATICS: THE REACTIVITY OF ALKYLAZOLES TOWARDS ELECTROPHILIC REAGENTS
Zayed, Salem E.,Aziz, Suzan Ibrahim,Erian, Ayman Wahba,Mohareb, Rafat Milad,Elmaged, Eiman I. Abou,et al.
, p. 51 - 58 (2007/10/02)
Several new condensed thiadiazoles and thiazoles are synthesized.The reactivity of alkylazoles towards electrophilic reagents is reported.New synthesis of thienylthiadiazoles, thiadiazolopyridines and pyridazines could be achieved.Key words: Thiazoles and thiadiazoles, alkylheteroaromatics, and nucleophilic reagents and alkylazoles.
The Reaction of Isothiocyanates with 2-Cyanoethanoic Acid Hydrazide. A Novel Synthesis of 1,3,4-Thiadiazoles
Elmoghayar, Mohamed Rifaat Hamza,Abdalla, Sanaa Osman,Nasr, Mohamed Yousry Abdel-Samad
, p. 781 - 784 (2007/10/02)
Benzoyl and ethoxycarbonyl isothiocyanates reacted with 2-cyanoethanoic acid hydrazide 2 to afford 1-cyanoacetyl-4-substituted thiosemicarbazide (5a,b).Compound 5a afforded the pyrazolo-s-triazine derivative 6 on treatment with 5percent potassium h
