93371-30-3

Usage

Uses

Used in Pharmaceutical Synthesis:
(S)-3-(Boc-aMino)-1-chloro-2-butanone is used as a building block for the synthesis of pharmaceuticals and other biologically active compounds. Its Boc-protected amino group and chlorine atom allow for versatile reactions and the creation of complex organic molecules, making it a valuable component in drug development.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-3-(Boc-aMino)-1-chloro-2-butanone is used as a key intermediate for the preparation of various organic compounds. Its unique structure facilitates a range of chemical reactions, contributing to the synthesis of specialty chemicals and advanced materials.

Upstream product

• 28875-17-4 (S)-N-(tert-butoxycarbonyl)alanine methyl ester 
• 3926-62-3 sodium monochloroacetic acid 
• 67919-80-6 (S)-3-[(tert-butoxy)carbonylamino]-1-diazobutan-2-one 
• 593-71-5 Chloroiodomethane 
• 51814-53-0 N-tert-butoxycarbonyl-L-alanine ethyl ester 

Downstream Products

• 165683-88-5 (S)-1-<(S)-1-(tert-butoxycarbonylamino)ethyl>oxirane 
• 126027-07-4 tert-butyl N-[(1S)-1-methyl-2-oxo-propyl]carbamate 

Relevant academic research and scientific papers

SUBSTITUTED 3-AZABICYCLO[3.1.0]HEXANES AS KETOHEXOKINASE INHIBITORS

Provided herein are substituted 3-azabicyclo[3.1.0]hexanes as ketohexokinase inhibitors, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.

Synthesis and γ-secretase activity of APP substrate-based hydroxyethylene dipeptide isosteres

Two new APP substrate-based hydroxyethylene isosteres (AT and VI) were prepared and their dipeptide conjugates shown not to inhibit the γ-secretase-mediated formation of either Aβ1-40 or Aβ1-42. The FG isostere and a des-hydroxy hydroxyethylene isostere a

A practical method for the preparation of α'-chloroketones of N-carbanaate protected-α-aminoacids

A practical method for the preparation of α-N-BOC-epoxides from protected amino acid esters based on the Kowalski homologation reaction is described. This procedure can be readily performed on a large scale without the use of hazardous reagents and has allowed preparation of epoxides 3 in multi-kilogram quantities.

Use of diamino ketones as analgesic agents

An enkephalin-degrading aminopeptidase enzyme is inhibited by compounds having the formula STR1 and pharmaceutically acceptable salt thereof, wherein R1 and R2 are each independently hydrogen, alkyl, carboxyalkyl, halo substituted al