933779-72-7Relevant academic research and scientific papers
Synthesis of 1,2,3,4,5,6,7,10-octahydro-1,5-imino-7,10-dioxo-3-benzazocine-4-carbonitrile derivative and evaluation of antitumor activity related to saframycin and renieramycin isoquinolinequinones
Koizumi, Yu-ichi,Inamura, Ken-ichi,Kubo, Akinori,Saito, Naoki
, p. 477 - 490 (2007/10/03)
3-Benzyl-1,2,3,4,5,6,7,10-octahydro-9-methoxy-8,11-dimethyl-7,10-dioxo-1,5-imino-3-benzazocine-4-carbonitrile (4) as a simple model of saframycin A and renieramycin M is prepared and its cytotoxicity tested against three human cancer cell lines.
