933784-97-5

Basic information

• Product Name: 5-fluoro-4-(2-Methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-iMidazol-5-yl)pyriMidin-2-aMine
• Synonyms: 5-fluoro-4-(2-Methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-iMidazol-5-yl)pyriMidin-2-aMine;5-fluoro-4-[2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl]-2-Pyrimidinamine
• CAS NO: 933784-97-5
• Molecular Formula: C₁₃H₁₆FN₅O
• Molecular Weight: 277.2974432
• Mol File: 933784-97-5.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-fluoro-4-(2-Methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-iMidazol-5-yl)pyriMidin-2-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-fluoro-4-(2-Methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-iMidazol-5-yl)pyriMidin-2-aMine(933784-97-5)
• EPA Substance Registry System: 5-fluoro-4-(2-Methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-iMidazol-5-yl)pyriMidin-2-aMine(933784-97-5)

Safety Data

• Hazardous Substances Data: 933784-97-5(Hazardous Substances Data)

Upstream product

• 110-91-8 morpholine 
• 133059-43-5 4-bromo-3-fluorobenzaldehyde 

Downstream Products

• 1252575-59-9 5-fluoro-N-(2-fluoro-4-(morpholinomethyl)phenyl)-4-(2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)pyrimidin-2-amine 
• 1252575-64-6 N-(2,5-difluoro-4-(morpholinomethyl)phenyl)-5-fluoro-4-(2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)pyrimidin-2-amine 
• 1252575-67-9 N-(2,5-difluoro-4-(morpholinomethyl)phenyl)-5-fluoro-4-(2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)pyrimidin-2-amine hydrochloride 
• 1252575-63-5 N-(4-(((3S,5S)-3,5-dimethylmorpholino)methyl)-2-fluorophenyl)-5-fluoro-4-(2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)pyrimidin-2-amine hydrochloride 
• 1252575-70-4 N-(4-(((3S,5S)-3,5-dimethylmorpholino)methyl)-2,5-difluorophenyl)-5-fluoro-4-(2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)pyrimidin-2-amine 
• 1252575-62-4 5-fluoro-N-(2-fluoro-4-(((S)-3-methylmorpholino)methyl)phenyl)-4-(2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)pyrimidin-2-amine hydrochloride 
• 1252575-61-3 5-fluoro-N-(2-fluoro-4-(((R)-3-methylmorpholino)methyl)phenyl)-4-(2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)pyrimidin-2-amine hydrochloride 
• 1252575-68-0 N-(2,5-difluoro-4-(((S)-3-methylmorpholino)methyl)phenyl)-5-fluoro-4-(2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)pyrimidin-2-amine 
• 1373233-54-5 2-(2,5-difluoro-4-(5-fluoro-4-(2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazol-5-yl)pyrimidin-2-ylamino)benzylamino)ethanol 

Relevant articles and documents

Imidazole Substituted Pyrimidines

A compound of formula (I) wherein R1 is hydrogen or fluoro; R2 and R3 are independently selected from hydrogen or methyl, or a pharmaceutically acceptable salt thereof; pharmaceutical formulations containing said compound; the use of said compound in therapy; the use for the treatment of conditions associated with glycogen synthase kinase-3 related disorders, such as Alzheimer's disease, as well as methods of treatment of said disorders, comprising administering to subjects in need of such treatment, a therapeutically effective amount of said compound.