93395-16-5

Basic information

• Product Name: 2(3H)-Furanone,dihydro-3,4-bis[(3,4,5- trimethoxyphenyl)methyl]-,(3R,4R)-
• CAS NO: 93395-16-5
• Molecular Weight: 446.497
• Mol File: 93395-16-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 2(3H)-Furanone,dihydro-3,4-bis[(3,4,5- trimethoxyphenyl)methyl]-,(3R,4R)- (CAS DataBase Reference)
• NIST Chemistry Reference: 2(3H)-Furanone,dihydro-3,4-bis[(3,4,5- trimethoxyphenyl)methyl]-,(3R,4R)- (93395-16-5)
• EPA Substance Registry System: 2(3H)-Furanone,dihydro-3,4-bis[(3,4,5- trimethoxyphenyl)methyl]-,(3R,4R)- (93395-16-5)

Safety Data

• Hazardous Substances Data: 93395-16-5(Hazardous Substances Data)

Upstream product

• 110397-80-3 (E)-α-(3,4,5-trimethoxybenzylidene)-β-(3,4,5-trimethoxybenzyl)-γ-butyrolactone 
• 65171-10-0 (+/-)-4-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2(3H)-furanone 
• 21852-50-6 3,4,5-trimethoxybenzyl bromide 
• 119239-40-6 (R)-(+)-methyl α-(3,4,5-trimethoxybenzyl)hemisuccinate 
• 119138-93-1 (+/-)-4-(3,4,5-trimethoxyphenyl)-3-methoxycarbonylbutanoic acid 
• 76763-88-7 (R)-dihydro-4-(3,4,5-trimethoxybenzyl)furan-2(3H)-one 
• 186581-53-3 diazomethane 
• 112667-54-6 (2R,3R)-3-(4'-hydroxy-3',5'-dimethoxybenzyl)-2-(3'',4''.5''-trimethoxybenzyl)-γ-butyrolactone 
• 84736-30-1 (trimethoxy-3,4,5 benzylidene) α-hemisuccinate de methyle 
• 93395-16-5 (3S*,4R*)-3-(3,4,5-trimethoxybenzyl)-4-(3,4,5-trimethoxybenzyl)-4,5-dihydro-2(3H)-furanone 
• 145432-29-7 (Z)-3-(Tetrahydro-pyran-2-yloxymethyl)-2-(3,4,5-trimethoxy-benzyl)-4-(3,4,5-trimethoxy-phenyl)-but-2-enoic acid methyl ester 
• 145432-33-3 (E)-3-(Tetrahydro-pyran-2-yloxymethyl)-2-(3,4,5-trimethoxy-benzyl)-4-(3,4,5-trimethoxy-phenyl)-but-2-enoic acid methyl ester 
• 95238-05-4 2-(Diethoxy-phosphoryl)-3-(3,4,5-trimethoxy-phenyl)-propionic acid methyl ester 
• 3840-31-1 (3,4,5-trimethoxyphenyl)methanol 

Downstream Products

• 50544-08-6 5,5'-(2,3-dimethylbutane-1,4-diyl)bis(1,2,3-trimethoxybenzene) 
• 50544-08-6 5,5'-(2,3-dimethylbutane-1,4-diyl)bis(1,2,3-trimethoxybenzene) 
• 93395-16-5 (3R*,4R*)-3-(3,4,5-trimethoxybenzyl)-4-(3,4,5-trimethoxybenzyl)-4,5-dihydro-2(3H)-furanone 
• 115495-67-5 (2R*,3S*)-2,3-dihydroxymethyl-1,4-bis-(3,4,5-trimethoxyphenyl)butane 
• 115495-67-5 (2R*,3R*)-2,3-dihydroxymethyl-1,4-bis-(3,4,5-trimethoxyphenyl)butane 
• 860704-71-8 meso-2,3-bis(3,4,5-trimethoxybenzyl)-1,4-butanediol 
• 138306-22-6 trans-3,4-bis(3,4,5-trimethoxybenzyl)tetrahydrofuran 
• 61281-38-7 (M*,6R*,7R*)-5,6,7,8-tetrahydro-6,7-dimethyl-1,2,3,10,11,12-hexamethoxy-dibenzocyclooctene 
• 14335-63-8 (1α,2β,3α)-6,7,8-trimethoxy-2,3-dimethyl-1-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydronaphthalene 
• 61281-38-7 (+/-)-1,2,3,10,11,12-hexamethoxy-r-6,t-7-dimethyl-5,6,7,8-tetrahydrodibenzocyclooctene 
• 115495-69-7 (2R*,3S*)-2,3-(methylsulfonyloxymethyl)-1,4-bis-(3,4,5-trimethoxyphenyl)butane 
• 14335-63-8 (1α,2β,3β)-6,7,8-trimethoxy-2,3-dimethyl-1-(3,4,5-trimethoxyphenyl)-1,2,3,4-tetrahydronaphthalene 

Relevant articles and documents

Simple synthesis of trans-α,β-dibenzyl-γ-butyrolactone lignans by diastereoselective reduction of α-benzylidene-β-benzyl-γ-butyralactones using NaBH4-NiCl2

trans-α,β-Dibenzyl-γ-butyrolactone lignans were synthesized by stereoselective reduction of α-benzylidene-β-benzyl-γ-butyrolactones using NaBH4-NiCl2. The reduction is found to proceed via conjugate addition of a hydride to an α-benz

STEREOSELECTIVE SYNTHESIS OF METHOXY SUBSTITUTED 2,3-DIBENZYL-γ-BUTYROLACTONES USING ORGANIC PHOSPHONATES AS INTERMEDIATES

A stereoselective, short and convergent synthesis of methoxy substituted 2,3-dibenzyl-γ-butyrolactones was developed using organic phosphonates as key intermediates.

A SIMPLE PREPARATION OF (R)-(+)-β-(3,4,5-TRIMETHOXYBENZYL)-BUTANOLIDE, AND ITS USE IN THE TOTAL SYNTHESES OF NATURALLY OCCURRING DIBENZYLBUTANOLIDE LIGNANS

Resolution of methyl α-(3,4,5-trimethoxybenzyl)hemisuccinate by means of (-)-ephedrine, followed by calcium borohydride reduction, afforded (R)-(+)-β-(3,4,5-trimethoxybenzyl)butanolide.This lactone was used as a starting material for the optically active