934-86-1Relevant academic research and scientific papers
Synthesis of novel restricted diamines; 2-(1-aminocycloalkan-1- yl)ethylamines
Suzuki, Takeshi,Imanishi, Naoki,Itahana, Hirotsune,Watanuki, Susumu,Ohta, Mitsuaki,Mase, Toshiyasu
, p. 701 - 712 (2007/10/03)
Novel restricted diamines, 2-(1-aminocycloalkan-1-yl)ethylamines 1,were prepared by using Michael addition of ethyl cyclohexylideneacetate 2 and cycloalkylideneacetonitriles 7 with amines. In Michael addition, ester 2 needed high reaction temperature and gave several products, whereas 7 reacted smoothly and gave 2-(1-amino-1-cyclohexyl)acetonitriles 8 in good yield (NH3 85%, MeNH2 89%, EtNH2 80%) and were easily convened to diamines 1.
