934016-71-4

Upstream product

• 934016-57-6 (R)-(-)-benzyl-5-(dimethoxyphosphoryl)-4-oxo-2-phenyl-3,4-dihydropyridine-1-carboxylate 
• 2234-82-4 1-propylmagnesium chloride 
• 814256-31-0 dimethyl (S_S,R)-(+)-2-oxo-4-(p-toluenesulfinylamino)-4-phenyl-butylphosphonate 
• 1027425-99-5 (4-oxo-6-phenyl-1,4,5,6-tetrahydro-pyridin-3-yl)-phosphonic acid dimethyl ester 

Downstream Products

• 934016-74-7 (2S,6R)-(+)-benzyl 2-propyl-6-phenyl-5,6-dihydropyridine-1-carboxylate 
• 934016-63-4 (2S,6R)-(+)-benzyl 2-propyl-6-phenylpiperidine-1-carboxylate 
• 934016-73-6 (2S,6R)-(+)-benzyl 3-(dimethoxyphosphoryl)-4-hydroxy-6-phenyl-2-propylpiperidine-1-carboxylate 

Relevant academic research and scientific papers

Asymmetric synthesis of ring functionalized trans-2,6-disubstituted piperidines from N-sulfinyl δ-amino β-keto phosphonates. Total synthesis of (-)-myrtine

Sulfinimine-derived N-sulfinyl δ-amino β-ketophosphonates are transformed via the enaminones to the phosphoryl dihydropyridones that selectively give trans-2,6-disubstituted 1,2,5,6-tetrahydropyridines on organocuprate addition and dephosphorylation.