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93414-04-1

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93414-04-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 93414-04-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,3,4,1 and 4 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 93414-04:
(7*9)+(6*3)+(5*4)+(4*1)+(3*4)+(2*0)+(1*4)=121
121 % 10 = 1
So 93414-04-1 is a valid CAS Registry Number.

93414-04-1Downstream Products

93414-04-1Relevant articles and documents

CRYSTAL FORMS OF O-DESMETHYLVENLAFAXINE FUMARATE

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Page/Page column 4, (2011/10/12)

Provided are crystalline forms of O-desmethylvenlafaxine fumarate, methods for their preparation, and pharmaceutical composition thereof.

A METHOD OF PREPARATION OF DESVENLAFAXINE AND ITS SALTS

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Page/Page column 8, (2010/06/17)

A method of preparation of 4-(2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl)phenol of formula (I), known under the generic name desvenlafaxine, and its pharmaceutically acceptable salts, which comprises (a) stirring up O-benzyl desvenlafaxine or its derivative of formula (II), or its salt, where R is selected from H, 4-methyl, 4-methoxy, 3,4-dimethoxy, 2-nitro, 4-nitro, 4-chloro, 4-bromo, 2,6-dichloro and 2,6-difluoro, in an organic solvent or a mixture of organic solvents, followed by dissolution of the starting substance at pH 3 to 8; (b) transformation of O-benzyl desvenlafaxine or its derivative of formula (II) to desvenlafaxine (I) by catalytic hydrogenation; (c) removing the catalyst from the desvenlafaxine solution with the pH value of 3 to 8 by filtration, followed by increasing pH to a value higher than 8 and lower than 11 by addition of an inorganic or organic base; (d) isolation of desvenlafaxine base (I) by filtration; and (e) transformation of desvenlafaxine base (I) to a pharmaceutically acceptable salt.

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