934170-59-9Relevant academic research and scientific papers
Synthetic studies toward clavilactone A: A concise access to,-substituted -butenolides by metathesis
Yasui, Hiroyuki,Yamamoto, Shun,Takao, Ken-ichi,Tadano, Kin-ichi
, p. 135 - 141 (2006)
Synthetic studies toward clavilactone A (1), using olefin metathesis as key steps, have been described. The ring-opening/ring-closing metathesis of 3bromo-2-[1-(1-cyclobutenyl)carboxyl-2-propenyl]-1,4-dimethoxybenzene (9) constructed a -arylated butenoiid
Total Synthesis of Clavilactones
Takao, Ken-Ichi,Mori, Kento,Kasuga, Kenya,Nanamiya, Ryuki,Namba, Ayumi,Fukushima, Yuuki,Nemoto, Ryuichi,Mogi, Takuma,Yasui, Hiroyuki,Ogura, Akihiro,Yoshida, Keisuke,Tadano, Kin-Ichi
, p. 7060 - 7075 (2018/07/15)
Clavilactones A, B, and D are epidermal growth factor receptor tyrosine kinase inhibitors that were isolated from cultures of the fungus Clitocybe clavipes. Here, we report full details of the total synthesis of these clavilactones. A key feature of our s
