934231-71-7Relevant academic research and scientific papers
Asymmetric synthesis of the 6-cyanoindole derivatives as non-steroidal glucocorticoid receptor modulators using (+)- and (-)-tert-butyl 6-cyano-3-[3-ethoxy-1,1,1-trifluoro-2-hydroxy-3-oxopropan-2-yl] -1H-indole-1-carboxylate
Sumiyoshi, Takaaki,Tojo, Kengo,Urabe, Daisuke,Tobe, Masanori
, p. 153 - 160 (2011)
We have successfully synthesized enantiomerically pure (+)- and (-)-tert-butyl 6-cyano-3-[3-ethoxy-1,1,1-trifluoro-2-hydroxy-3-oxopropan-2-yl]- 1H-indole-1-carboxylate (+)-1 and (-)-1, which are key intermediates of non-steroidal glucocorticoid receptor m
