93434-36-7

Usage

Derivative of benzoic acid

2-[2-(2-METHOXYPHENYL)ETHYL]BENZOIC ACID is derived from benzoic acid, which is a building block for many pharmaceuticals and a known anti-inflammatory agent.

2-Methoxyphenyl group attached to the ethyl chain

2-[2-(2-METHOXYPHENYL)ETHYL]BENZOIC ACID contains a 2-methoxyphenyl group attached to an ethyl chain, which is responsible for its structural similarities to other bioactive compounds.

Potential therapeutic agent

2-[2-(2-METHOXYPHENYL)ETHYL]BENZOIC ACID is used in pharmaceutical and medical research as a potential therapeutic agent due to its structural similarities to other bioactive compounds.

Potential anti-inflammatory and analgesic properties

2-[2-(2-METHOXYPHENYL)ETHYL]BENZOIC ACID has been investigated for its potential to reduce inflammation and relieve pain.

Subject of interest in drug development and medicinal chemistry research

The structure and properties of 2-[2-(2-METHOXYPHENYL)ETHYL]BENZOIC ACID make it a subject of interest in the field of drug development and medicinal chemistry research.

Upstream product

• 85164-39-2 3-(2-methoxyphenylmethyl)isobenzofuran-1(3H)-one 
• 93012-04-5 2?(3-methoxystyryl)benzoic acid 
• 586-38-9 3-Methoxybenzoic acid 
• 85164-33-6 trans-2'-methoxystilbene-2-carboxylic acid 

Downstream Products

• 17910-73-5 2-hydroxy-10,11-dihydro-5H-dibenzocyclohepten-5-one 

Relevant academic research and scientific papers

(R, S)-2-[ [5-(9- [...] carbonyl amino) dibenzo [A, D] cyclohepta-2-yl] oxy] acetic acid synthesis process (by machine translation)

The invention relates to a (R, S)-2-[ [5-(9- [...] carbonyl amino) dibenzo [A, D] cyclohepta-2-yl] oxy] acetic acid synthesis process, comprising the following steps: step one, O-carboxybenzaldehyde and Intergovernmental methoxylphenylboronic acetic acid in anhydrous sodium acetate under the catalysis of the reaction to obtain 2-(3-methoxy-vinyl) benzoic acid, Pd-C under the catalysis of the hydrogen reduction reaction-; step two, and SOCl 2 reaction to obtain 2-methoxy -10, 11-dihydro -5H-dibenzo [a, d] cycloheptene-5-one, then anhydrous AlCl 3 catalytic reflux reaction; step three, the return reaction of the intermediate product and bromine second grade acid benzyl ester for reaction; step four, the reduction reaction of the hydrogen gas, and then with Fmoc-NH 2 for reaction, to obtain. This invention, through optimization of the catalyst, is obviously improved the overall yield, effectively reducing the cost, is suitable for industrial mass synthesis application. (by machine translation)

Dibenzosuberyl and dibenzosuberenyl derivatives

The present invention is directed to a compound represented by the following formula (I), STR1 and a linker for peptide synthesis using the above compound. When the linker of the present invention is used for the solid-phase peptide synthesis, it is possible to synthesize those peptides which are sensitive to acid and difficult to synthesize by conventional methods. Also, side reactions can be prevented, and the desired product is produced at a high purity because cleavage can be achieved under milder conditions or in shorter times. In other words, efficient peptide synthesis is possible.