934342-39-9

Basic information

• Product Name: 3-Fluoro-1,3-piperidinedicarboxylic acid 1-tert-butyl ester
• Synonyms: 3-Fluoro-1,3-piperidinedicarboxylic acid 1-tert-butyl ester;1-Boc-3-fluoropiperidine-3-carboxylic Acid;1-Boc-3-fluoropiperidine-...;1-Boc-3-fluoropiperidine-3-Carbocylic acid;3-fluoro-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-3-carboxylic acid
• CAS NO: 934342-39-9
• Molecular Formula: C₁₁H₁₈FNO₄
• Molecular Weight: 247.27
• Mol File: 934342-39-9.mol

Chemical Properties

• Boiling Point: 346℃
• Flash Point: 163℃
• Appearance: /
• Density: 1.22
• Storage Temp.: 2-8°C
• PKA: 2.41±0.20(Predicted)
• CAS DataBase Reference: 3-Fluoro-1,3-piperidinedicarboxylic acid 1-tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Fluoro-1,3-piperidinedicarboxylic acid 1-tert-butyl ester(934342-39-9)
• EPA Substance Registry System: 3-Fluoro-1,3-piperidinedicarboxylic acid 1-tert-butyl ester(934342-39-9)

Safety Data

• Hazardous Substances Data: 934342-39-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3-Fluoro-1,3-piperidinedicarboxylic acid 1-tert-butyl ester is used as an intermediate compound for the synthesis of various pharmaceutical products. Its stable fluorine atom and ester functional groups contribute to the development of new drug molecules with improved properties, such as enhanced bioavailability and targeted delivery.
Used in Chemical Research:
In the field of chemical research, 3-Fluoro-1,3-piperidinedicarboxylic acid 1-tert-butyl ester serves as a valuable compound for studying the effects of fluorination and esterification on the chemical properties and reactivity of piperidine derivatives. This knowledge can be applied to the design of new chemical entities with specific functionalities and applications.
Used in Material Science:
3-Fluoro-1,3-piperidinedicarboxylic acid 1-tert-butyl ester is used as a building block in the development of new materials with unique properties. Its resistance to oxidation and degradation, along with its potential for forming stable bonds, makes it a promising candidate for the creation of advanced materials in various industries, such as electronics, coatings, and adhesives.

Upstream product

• 934342-31-1 3-fluoropiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester 
• 148763-41-1 1-(tert-butyl) 3-methyl piperidine-1,3-dicarboxylate 

Downstream Products

• 934342-31-1 3-fluoropiperidine-1,3-dicarboxylic acid 1-tert-butyl ester 3-methyl ester 
• 1209781-11-2 tert-butyl 3-fluoro-3-(hydroxymethyl)piperidine-1-carboxylate 

Relevant articles and documents

N-ACYL PYRIDINE BIARYL COMPOUNDS AND THEIR USES

The present invention provides a compound of general formula:wherein Z2-Z6 include one or two nitrogen atoms as described herein, including pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. These compounds inhibit the activity of CDK9 and are thus useful as pharmaceuticals. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds of Formula I and isomers thereof, and pharmaceutical compositions comprising such compounds.

N-ACYL PYRIMIDINE BIARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS

The present invention provides a compound of the general formula (1): wherein one of X and Y is N and the other is an optionally substituted carbon atom, and Z2-Z5 represent one or two nitrogen atoms, as further described herein, including pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. These compounds inhibit the activity of CDK9 and are thus useful as pharmaceuticals and as components of pharmaceutical compositions. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds described herein or pharmaceutical compositions comprising such compounds.

HETEROARYL COMPOUNDS AS KINASE INHIBITORS

The present invention provides a compound of Formula (I): and pharmaceutically acceptable salts thereof. Also provided is a method of using a compound of Formula I for treating a disease or condition mediated by a CDK inhibitor

PYRAZINYLPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES

The present invention provides a compound of Formula (I) and pharmaceutically acceptable salts thereof. Also provided is a method of using a compound of Formula I for treating a disease or condition mediated by a CDK inhibitor.