934370-86-2Relevant articles and documents
Method of preparing important intermediate 1-(9H-4-carbazoleoxy)-5-phenyl-2-pentanol of carvedilol
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Paragraph 0005; 0018; 0019; 0020; 0021; 0022; 0023-0029, (2017/05/23)
The invention discloses a method of preparing an important intermediate, 1-(9H-4-carbazoleoxy)-5-phenyl-2-pentanol (I), of carvedilol and mainly solves the problem of influence of a side product, dimer, generated during a process of preparing the compound
Synthesis of new oxazolidinonyl/oxazolidinyl carbazole derivatives for β- blocking activity
Anumula, Raghupathi Reddy,Kagga, Mukkanti,Ghanta, Mahesh Reddy,Padi, Pratap Reddy
experimental part, p. 187 - 194 (2009/04/06)
Preparation of some new carbazolyloxy propanolamine derivatives and their cyclization into corresponding oxazolidinonyl/oxazolidinyl carbazole derivatives were described.
Novel heterocyclic compounds as pSTAT3/IL-6 inhibitors
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Page/Page column 15, (2010/11/27)
The present invention relates to novel heterocyclic compounds of the general formula (I), as IL-6 inhibitors, their derivatives, their analogs, their tautomeric forms, their stereoisomers, their polymorphs, their hydrates, their solvates, their pharmaceutically acceptable salts and compositions, their metabolites and prodrugs thereof. The present invention more particularly provides novel heterocyclic compounds of the general formula (I). Also included is a method for treatment of cancer, cancer cachexia and inflammatory diseases including immunological diseases, particularly those mediated by cytokines such as IL-6, through pSTAT3 inhibition, in a mammal comprising administering an effective amount of a compound of formula (I) as described above.
