Welcome to LookChem.com Sign In|Join Free

CAS

  • or

72955-94-3

Post Buying Request

72955-94-3 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

72955-94-3 Usage

Chemical Properties

Off-White Solid

Uses

Different sources of media describe the Uses of 72955-94-3 differently. You can refer to the following data:
1. Labelled Carvedilol
2. N-Benzyl Carvedilol (Carvedilol EP Impurity C) is an impurity of Carvedilol (C184625) and a degradation product in Carvedilol tablets.

Check Digit Verification of cas no

The CAS Registry Mumber 72955-94-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,9,5 and 5 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 72955-94:
(7*7)+(6*2)+(5*9)+(4*5)+(3*5)+(2*9)+(1*4)=163
163 % 10 = 3
So 72955-94-3 is a valid CAS Registry Number.
InChI:InChI=1/C31H32N2O4/c1-35-28-15-7-8-16-29(28)36-19-18-33(20-23-10-3-2-4-11-23)21-24(34)22-37-30-17-9-14-27-31(30)25-12-5-6-13-26(25)32-27/h2-17,24,32,34H,18-22H2,1H3

72955-94-3 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Sigma-Aldrich

  • (Y0000103)  Carvedilol impurity C  European Pharmacopoeia (EP) Reference Standard

  • 72955-94-3

  • Y0000103

  • 1,880.19CNY

  • Detail
  • USP

  • (1096655)  Carvedilol Related Compound C  United States Pharmacopeia (USP) Reference Standard

  • 72955-94-3

  • 1096655-20MG

  • 14,578.20CNY

  • Detail
  • Sigma-Aldrich

  • (41946)  (2RS)-1-{Benzyl[2-(2-methoxyphenoxy)ethyl]amino}-3-(9H-carbazol-4-yloxy)-2-propanol  ≥95.0% (HPLC), pharmaceutical impurity standard

  • 72955-94-3

  • 41946-50MG

  • 7,025.85CNY

  • Detail

72955-94-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-[benzyl-[2-(2-methoxyphenoxy)ethyl]amino]-3-(9H-carbazol-4-yloxy)propan-2-ol

1.2 Other means of identification

Product number -
Other names N-benzylcarvedilol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:72955-94-3 SDS

72955-94-3Downstream Products

72955-94-3Relevant articles and documents

Method for preparing carvedilol intermediate N-benzyl carvedilol

-

Paragraph 0012; 0022; 0023; 0024; 0025; 0026; 0027-0035, (2017/05/23)

The invention relates to a method for preparing a carvedilol intermediate N-benzyl carvedilol, wherein the method comprises the following steps: (1) firstly, loading a compound II, a compound III, sodium hydroxide and a solvent into a reaction kettle, heating up to a reaction temperature, and carrying out a vigorous stirring reaction, to obtain a reaction material liquid; (2) in the reaction process, pumping the reaction material liquid into an external circulation water removal system filled with a water removal agent at a certain flow velocity, and carrying out circulation water removal; and (3) after the reaction is finished, discharging a product I from the bottom of the reaction kettle, and recrystallizing to obtain a compound I. Compared with the prior art, water generated in the nucleophilic substitution reaction of the compound II and the compound III is removed timely by the external circulation water removal system, the conversion rate of the reaction raw materials of the compound II and the compound III is greatly increased, low-energy-consumption, simple and quick continuous production is achieved, the yield of the obtained reaction product I is more than 90%, and the chemical purity is more than 97%.

PROCESS FOR PREPARATION OF 1-(9H-CARBAZOL-4-YLOXY)-3-[[2-(2- METHOXYPHENOXY) ETHYL] AMINO]-2-PROPANOL

-

Page/Page column 11-12, (2009/10/22)

The present invention relates to a process for preparation of l-(9H-carbazol-4-yloxy)-3- [[2-(2-methoxyphenoxy) ethyl] amino]-2-propanol and its salts comprising; a)reacting 1- (9H-carbazol-4-yloxy)-3-arylmethylamino-2-propanol or its 9-substituted derivatives with 2-(2-methoxyphenoxy)-haloethane; and b) deprotecting the resulting intermediate to obtain l-(9H-carbazol— 4— yloxy)-3-[[2-(2-methoxyphenoxy)ethyl] amino]-2-propanol in free form or its acid addition salt, which are pharmaceutically valuable compounds.

A PROCESS FOR PREPARATION OF 1-[9H-CARBAZOL-4-YLOXY]- 3-[{2-(2-(-(METHOXY)PHENOXY)-ETHYL}-AMINO]-PROPAN-2-OL

-

Page 13; 17-18, (2008/06/13)

The present invention provides a process for preparation of 1-[9H-carbazol-4-yloxy]-3-[{2-(2-(methoxy)phenoxy)-ethyl}-amino]-propan-2-ol, a compound of formula 1 in racemic form or in the form of optically active R or S enantiomer or its pharmaceutically acceptable salt, comprising, reacting 4-(oxiranylmethoxy)-9H-carbazole, a compound of formula (2) or the R or S enantiomer thereof with a compound of formula (5), wherein R1 is benzyl or substituted benzyl group, in an aprotic organic solvent in presence of a catalyst to obtain a compound of formula (6), or the R or S enantiomer thereof, wherein R1 is as defined above. The resultant compound of formula (6) is subjected to debenzylation reaction by catalytic hydrogenation to obtain the compound of formula (1), if desired converting the resultant compound of formula (1) to a pharmaceutically acceptable salt thereof.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 72955-94-3