934495-35-9Relevant academic research and scientific papers
Improved Synthesis of First Cell-Permeable Allosteric PTPRZ Inhibitor NAZ2329
Chen, Weiming,Hu, Wei,Zeng, Qiang
, p. 2095 - 2100 (2021/11/13)
Abstract: NAZ2329 is the first cell-permeable small molecular allosteric inhibitor of protein tyrosine phosphatase receptor–type Z (PTPRZ), which was considered as a new potential molecular target for drug development in glioblastoma. A facile and high-ef
METHYLPYRROLOPYRIMIDINECARBOXAMIDES
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Page/Page column 105, (2012/06/18)
The compounds of Formula (I), wherein R1, R2, R21, R22, R23, R24, Y and R3 have the meanings as given in the description, the salts thereof, the stereoisomers of the compounds and the salts thereof are effective inhibitors of the type 5 phosphodiesterase.
METHYLPYRROLOPYRIMIDINECARBOXAMIDES
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Page/Page column 169, (2011/04/14)
The compounds of formula (I) wherein R1, R2, R21, R22, R23, R24, Y and R3 have the meanings as given in the description, the salts thereof, and the stereoisomers of the compounds and the salts thereof are effective inhibitors of the type 5 phosphodiestera
Pyrazole derivatives, compositions containing such compounds and methods of use
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Page/Page column 20-21, (2010/11/26)
Pyrazoles having a naphthyl group attached are disclosed. The compounds are useful for treating type 2 diabetes and related conditions. Pharmaceutical compositions and methods of treatment are also included.
