934536-73-9Relevant academic research and scientific papers
Palladium-Catalyzed Asymmetric Intramolecular Reductive Heck Desymmetrization of Cyclopentenes: Access to Chiral Bicyclo[3.2.1]octanes
Yuan, Zhenbo,Feng, Ziwen,Zeng, Yuye,Zhao, Xiaobin,Lin, Aijun,Yao, Hequan
supporting information, p. 2884 - 2888 (2019/02/16)
A palladium-catalyzed asymmetric reductive Heck reaction of unactivated aliphatic alkenes, with eliminable β-hydrogen atoms, has been realized for the first time. A series of optically active bicyclo[3.2.1]octanes bearing chiral quaternary and tertiary carbon stereocenters were obtained in good yields with excellent enantioselectivities, exhibiting good functional-group tolerance and scalability. Moreover, deuterated optically active bicyclo[3.2.1]octanes were also obtained in high efficiency.
Palladium-catalyzed enantioselective cyclization of silyloxy-1,6-enynes
Corkey, Britton K.,Toste, F. Dean
, p. 2764 - 2765 (2007/10/03)
The enantioselective intramolecular addition of silyl enol ethers and silyl ketene aminals onto alkyne is described. The reaction employs DTBMSegphos-Pd(II) or Binaphane-Pd(II) complexes as catalysts for the formation of methylene cyclopentane adducts fro
