934548-35-3Relevant academic research and scientific papers
Synthesis of 3-substituted indazoles and benzoisoxazoles via Pd-catalyzed cyclization reactions: application to the synthesis of nigellicine
Inamoto, Kiyofumi,Katsuno, Mika,Yoshino, Takashi,Arai, Yukari,Hiroya, Kou,Sakamoto, Takao
, p. 2695 - 2711 (2007/10/03)
Syntheses of 3-substituted indazoles and benzoisoxazoles were efficiently accomplished with the aid of Pd-catalyzed intramolecular carbon-nitrogen and carbon-oxygen bond formations. The catalyst system described herein allows the cyclization to proceed under very mild conditions and thus could be applied to a wide range of substrates with acid- or base-sensitive functional groups. A total synthesis for the indazole ring-containing natural product nigellicine is also described.
Efficient synthesis of 3-substituted indazoles using Pd-catalyzed intramolecular amination reaction of N-tosylhydrazones
Inamoto, Kiyofumi,Katsuno, Mika,Yoshino, Takashi,Suzuki, Ikue,Hiroya, Kou,Sakamoto, Takao
, p. 1026 - 1027 (2007/10/03)
The efficient method for the preparation of 3-substituted indazoles was developed using the palladium catalyzed intramolecular animation reaction of 2-bromophenyl hydrazone derivatives. Good functional group compatibility was observed under mild reaction
