934619-04-2Relevant articles and documents
Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents
Flipo, Marion,Beghyn, Terence,Leroux, Virginie,Florent, Isabelle,Deprez, Benoit P.,Deprez-Poulain, Rebecca F.
, p. 1322 - 1334 (2007/10/03)
Proteases that are expressed during the erythocytic stage of Plasmodium falciparum are newly explored drug targets for the treatment of malaria. We report here the discovery of potent inhibitors of PfA-M1, a metallo- aminopeptidase of the parasite. These