934619-02-0

Basic information

• Product Name: (E)-3-phenyl-2-trityloxycarbamoylacrylic acid
• Synonyms: (E)-3-phenyl-2-trityloxycarbamoylacrylic acid
• CAS NO: 934619-02-0
• Molecular Weight: 449.506
• Mol File: 934619-02-0.mol

Chemical Properties

• CAS DataBase Reference: (E)-3-phenyl-2-trityloxycarbamoylacrylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-3-phenyl-2-trityloxycarbamoylacrylic acid(934619-02-0)
• EPA Substance Registry System: (E)-3-phenyl-2-trityloxycarbamoylacrylic acid(934619-02-0)

Safety Data

• Hazardous Substances Data: 934619-02-0(Hazardous Substances Data)

Upstream product

• 24302-12-3 (E)-2-(Ethoxycarbonyl)-3-phenylprop-2-enoic acid 
• 5292-53-5 diethyl benzalmalonate 
• 24302-10-1 2-[1-phenyl-(Z)-methylidene]malonic acid monoethyl ester 
• 934619-01-9 (Z)-3-phenyl-2-trityloxycarbamoylacrylic acid ethyl ester 

Downstream Products

• 934619-04-2 2-benzylidene-N-(4-phenyl-butyl)-N'-trityloxy-malonamide 
• 934619-03-1 2-benzylidene-N-(4-fluoro-benzyl)-N'-trityloxy-malonamide 

Relevant articles and documents

Structure-activity relationships and blood distribution of antiplasmodial aminopeptidase-1 inhibitors

Malaria is a severe infectious disease that causes between 655 000 and 1.2 million deaths annually. To overcome the resistance to current drugs, new biological targets are needed for drug development. Aminopeptidase M1 (PfAM1), a zinc metalloprotease, has

Novel selective inhibitors of the zinc plasmodial aminopeptidase PfA-M1 as potential antimalarial agents

Proteases that are expressed during the erythocytic stage of Plasmodium falciparum are newly explored drug targets for the treatment of malaria. We report here the discovery of potent inhibitors of PfA-M1, a metallo- aminopeptidase of the parasite. These