93464-95-0Relevant articles and documents
meso-2,5-Dimercapto-N,N,N',N'-tetramethyladipamide: A Readily Available, Kinetically Rapid Reagent for the Reduction of Disulfides in Aqueous Solution
Lees, Watson J.,Singh, Rajeeva,Whitesides, George M.
, p. 7328 - 7331 (2007/10/02)
meso-2,5-Dimercapto-N,N,N',N'-tetramethyladipamide (meso-DTA) reduces disulfide bonds up to 8 times faster (kinetic) than does dithiothreitol (DTT) in aqueous solution at pH 7.0. meso-DTA is easily synthesized in five steps (39percent overall yield) from adipic acid. meso-DTA, which forms a cyclic disulfide, is less reducing than DTT by approximately 56 mV, but is much more reducing than mercaptoethanol.