934660-67-0Relevant articles and documents
Preparation method of cobimetinib
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Paragraph 0028; 0032-0034; 0040; 0044; 0045; 0049; 0053, (2019/02/04)
The invention discloses a preparation method of cobimetinib. The preparation method comprises the following steps of (1) performing oxidative coupling cyclization on acetone and ammonia water under the conditions of catalysis by iodized salt and protonic
METHODS OF USING MEK INHIBITORS
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Page/Page column 370, (2008/12/06)
The present invention provides methods of treating cancer by administering a compound of Formula (I), or a pharmaceutically acceptable salt or solvate thereof, in combination with other cancer treatments.
AZETIDINES AS MEK INHIBITORS FOR THE TREATMENT OF PROLIFERATIVE DISEASES
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Page/Page column 202, (2008/06/13)
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