934765-62-5Relevant academic research and scientific papers
Phenazine N,N′-dioxide scaffold as selective hypoxic cytotoxin pharmacophore. Structural modifications looking for further DNA topoisomerase II-inhibition activity
Gonda, Mariana,Nieves, Marcos,Nunes, Elia,López De Ceráin, Adela,Monge, Antonio,Lavaggi, María Laura,González, Mercedes,Cerecetto, Hugo
, p. 595 - 607 (2013)
Phenazine-5,10-dioxides have been identified as prodrugs for antitumour therapy that undergo hypoxic-selective bioreduction, in the solid tumour cells, to form cytotoxic species. We investigated structural modifications of the phenazine-5,10-dioxide scaff
NOVEL HETEROCYCLE COMPOUNDS
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Page/Page column 34, (2009/04/24)
The present invention relates to novel compounds which are antagonist or inverse agonists at an opioid receptor. Such compounds are useful in the treatment of obesity and related diseases and/or conditions in mammals, particularly humans. Methods of making and using such compounds are also disclosed.
