93487-83-3Relevant academic research and scientific papers
N′-(Arylsulfonyl)pyrazoline-1-carboxamidines as novel, neutral 5-hydroxytryptamine 6 receptor (5-HT6R) antagonists with unique structural features
Van Loevezijn, Arnold,Venhorst, Jennifer,Iwema Bakker, Wouter I.,De Korte, Cor G.,De Looff, Wouter,Verhoog, Stefan,Van Wees, Jan-Willem,Van Hoeve, Martijn,Van De Woestijne, Rob P.,Van Der Neut, Martina A. W.,Borst, Alice J. M.,Van Dongen, Maria J. P.,De Bruin, Natasja M. W. J.,Keizer, Hiskias G.,Kruse, Chris G.
supporting information; experimental part, p. 7030 - 7054 (2011/12/15)
The 5-HT6 receptor (5-HT6R) has been in the spotlight for several years regarding CNS-related diseases. We set out to discover novel, neutral 5-HT6R antagonists to improve off-target selectivity compared to basic amine-con
PYRIDYL GUANIDINE ANTI-ULCER AGENTS
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, (2008/06/13)
Compounds of the formula STR1 wherein R 1 is a straight or branched chain alkynyl group containing from 3 to 9 carbon atoms, inclusive; R 2 is hydrogen, hydroxy, cyano, (lower)alkyl, (lower) alkoxy, halogen or amino; n is 2 or 3; X is NR 3 or CHR 3 ; R 3
