93490-31-4Relevant academic research and scientific papers
Synthese von natuerlichen Haloindolen via Hetero-Cope-Umlagerung von Vinyl-N-phenylhydroxamaten
Martin, Pierre
, p. 344 - 347 (2007/10/02)
An efficient method for the synthesis of natural 4-chloro-6-methoxyindole (the promutagen from fava beans) and of the two 4,6-dibromo- and 3,4,6-tribromoindoles (produced by acorn worms, Enteropneusta) is presented.The key step is a hetero-Cope rearrangem
Direct Acting, Highly Mutagenic, α-Hydroxy N-Nitrosamines from 4-Chloroindoles
Buechi, George,Lee, Gary C. M.,Yang, David,Tannenbaum, Steven R.
, p. 4115 - 4119 (2007/10/02)
Fave beans (Vicia fava) contain 4-chloro-6-methoxyindole, a promutagen, which on nitrosation under simulated gastric conditions forms 4-chloro-6-methoxy-2-hydroxy-N1-nitrosoindolin-3-one oxime, a direct-acting, exceedingdly potent, mutagen whic
