935-61-5

Basic information

• Product Name: Spiro[2.7]decan-4-one
• Synonyms: Spiro[2.7]decan-4-one
• CAS NO: 935-61-5
• Molecular Formula: C10H16O
• Molecular Weight: 152.23344
• Mol File: 935-61-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Spiro[2.7]decan-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: Spiro[2.7]decan-4-one(935-61-5)
• EPA Substance Registry System: Spiro[2.7]decan-4-one(935-61-5)

Safety Data

• Hazardous Substances Data: 935-61-5(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Tetrahedron Letters, 5, p. 3189, 1964 DOI: 10.1002/lipi.19640660210

Upstream product

• 502-49-8 cycloactanone 
• 25059-70-5 2-chloroethyl dimethyl sulfonium iodide 
• 185-87-5 spiro<2,7>decane 
• 286-60-2 bicyclo[6.1.0]nonane 
• 1108-70-9 2,2-Bis-tosyloxymethyl-cyclooctan-1-on 
• 941-21-9 2,2-Bis-brommethyl-cyclooctan-1-on 

Relevant articles and documents

Direct Oxidation of Cyclopropanated Cyclooctanes as a Synthetic Approach to Polycyclic Cyclopropyl Ketones

A series of polycyclic hydrocarbons containing cyclopropane moieties 1,2-annelated or spiro-condensed with a cyclooctane ring were investigated under oxidative conditions. Four oxidizing systems (O3 on SiO2, a dioxirane derived from trifluoroacetone, CrO3, and RuO4, generated in situ), were tested to evaluate and compare their reactivity and usefulness. RuO4 was found to be the best of them, considering its oxidative power together with the simple operating procedure. Conditions for the specific oxidation of polycyclic hydrocarbons were found. New cyclooctane derivatives containing cyclopropyl carbonyl moieties were obtained.

2-CHLOROETHYL DIMETHYL SULFONIUM IODIDE.

Ketones are readily spiroannelated by 2-chloroethyldimethyl sulfonium iodide 1 in the presence of t-butoxide anion in t-butanol.The procedure affords a simple one step spirocyclopropanation of ketones in good yields.