93517-75-0Relevant academic research and scientific papers
Chemoselectivity of 2-arylmethyleneaminoisoindolin-1,3-diones toward arenes under friedel-crafts conditions: An efficient synthesis of benzophenones integrated with 2-substituted hydrazone moieties
Derbala, Hamed A.
experimental part, p. 700 - 704 (2012/08/27)
Treatment 2-arylmethyleneaminoisoindole-1,3-diones 1a-c with arenes in the presence of AlCl3-DMF complex as a catalyst afforded the novel compounds, 2-((arylidenehydrazono)(aryl)-methyl)benzophenones 3a-n in satisfactory yields. The structure of the obtained products 3a-n was confirmed by the use of IR, 1H-NMR, 13C-NMR, mass spectra, and elemental analyses.
POTASSIUM CHANNEL MODULATORS
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Page/Page column 43, (2011/06/19)
Disclosed herein are KCNQ potassium channels modulators of formula (I) wherein ring Z1, R1, p, R3, and R4 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.
NEW CONVENIENT ONE-STEP SYNTHESIS OF 4-ARYLPHTHALAZ-1-ONES
Ismail, M. Fekry,El-Bassiouny, F. A.,Younes, H. A.
, p. 2983 - 2984 (2007/10/02)
4-Arylphthalaz-1-ones (2a-e) are prepared by the hitherto unknown reaction of N-aminophthalimide (1) with aromatic hydrocarbons under Friedel-Crafts conditions.The reaction of N-aminophthalimide with Grignard reagents presents another convenient method for the synthesis of 4-alkyl or 4-arylphthalaz-1-ones.
