93517-76-1Relevant academic research and scientific papers
TOLL-LIKE RECEPTOR 8 (TLR8)-SPECIFIC ANTAGONISTS AND METHODS OF MAKING AND USES THEREOF
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Page/Page column 51; 52, (2019/05/22)
Toll-like receptor 8 (TLR8)-specific inhibitors and methods of using the same in individuals having an autoimmune disease or an inflammatory disorder.
REACTIONS OF 2,3-DIARYL-3-HYDROXYPHTHALIMIDINES WITH GRIGNARD REAGENTS AND HYDRAZINE HYDRATE
Ismail, Mohamed Fekry,Enayat, Ebtesam Ismail,El-Bassiouny, Fakhry Abdel Aziz,Younes, Hamed Ahmed
, p. 677 - 678 (2007/10/02)
2,3-diaryl-3-hydroxyphthalimidines, 1, react with benzylmagnesium chloride to give 3-aryl-3-benzylphthalides 2.The reaction involves the removal of the amine part at position 2.Reaction of 1a with phenylmagnesium bromide proceeded differently to give 3.Th
NEW CONVENIENT ONE-STEP SYNTHESIS OF 4-ARYLPHTHALAZ-1-ONES
Ismail, M. Fekry,El-Bassiouny, F. A.,Younes, H. A.
, p. 2983 - 2984 (2007/10/02)
4-Arylphthalaz-1-ones (2a-e) are prepared by the hitherto unknown reaction of N-aminophthalimide (1) with aromatic hydrocarbons under Friedel-Crafts conditions.The reaction of N-aminophthalimide with Grignard reagents presents another convenient method for the synthesis of 4-alkyl or 4-arylphthalaz-1-ones.
