935290-76-9Relevant articles and documents
Asymmetric synthesis of conformationally constrained trans-2,3-piperidine- dicarboxylic acid derivatives
Zhuo, Jincong,Burns, David M.,Zhang, Colin,Xu, Meizhong,Weng, Lingkai,Qian, Ding-Quan,He, Chunhong,Lin, Qiyan,Li, Yun-Long,Shi, Eric,Agrios, Costas,Metcalf, Brian,Yao, Wenqing
, p. 460 - 464 (2008/01/06)
An efficient asymmetric synthesis of conformationally constrained (2S,3S)-piperidinedicarboxylic acid derivatives starting from L-aspartic acid β-tert-butyl ester and 3-chloro-2-(chloromethyl)-1-propene is described. The key steps involve N-alkylation of