935445-90-2

Basic information

• Product Name: 3-(acetylamino)-4-(4-methoxyphenyl)-6-methyl-N⁵-{4-[(pyrimidin-2-ylamino)sulfonyl]phenyl}-N²-(4-chlorophenyl)thieno[2,3-b]pyridine-2,5-dicarboxamide
• CAS NO: 935445-90-2
• Molecular Weight: 742.236
• Mol File: 935445-90-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(acetylamino)-4-(4-methoxyphenyl)-6-methyl-N⁵-{4-[(pyrimidin-2-ylamino)sulfonyl]phenyl}-N²-(4-chlorophenyl)thieno[2,3-b]pyridine-2,5-dicarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(acetylamino)-4-(4-methoxyphenyl)-6-methyl-N⁵-{4-[(pyrimidin-2-ylamino)sulfonyl]phenyl}-N²-(4-chlorophenyl)thieno[2,3-b]pyridine-2,5-dicarboxamide(935445-90-2)
• EPA Substance Registry System: 3-(acetylamino)-4-(4-methoxyphenyl)-6-methyl-N⁵-{4-[(pyrimidin-2-ylamino)sulfonyl]phenyl}-N²-(4-chlorophenyl)thieno[2,3-b]pyridine-2,5-dicarboxamide(935445-90-2)

Safety Data

• Hazardous Substances Data: 935445-90-2(Hazardous Substances Data)

Upstream product

• 134477-88-6 3-oxo-N-{4-[(pyrimidin-2-ylamino)sulphonyl]phenyl}butanamide 
• 68-35-9 sulfadiazine 
• 935445-82-2 ethyl 3-amino-4-(4-methoxyphenyl)-6-methyl-5-[({4-[(pyrimidin-2-ylamino)sulfonyl]phenyl}amino)carbonyl]thieno[2,3-b]pyridine-2-carboxylate 
• 935445-72-0 {3-cyano-4-(4-methoxy-phenyl)-6-methyl-5-[4-(pyrimidin-2-ylsulfamoyl)-phenylcarbamoyl]-pyridin-2-ylsulfanyl}-acetic acid ethyl ester 
• 935445-52-6 5-cyano-4-(4-methoxyphenyl)-2-methyl-N-{4-[(pyrimidin-2-ylamino)sulfonyl]phenyl}-6-thioxo-1,6-dihydropyridine-3-carboxamide 
• 106-47-8 4-chloro-aniline 

Relevant articles and documents

Acetoacetanilides in heterocyclic synthesis, Part 1: An expeditious synthesis of thienopyridines and other fused derivatives

3-Oxo-N-{4-[(pyrimidin-2-ylamino)sulfonyl]phenyl}butanamide 1 reacts with arylidinecyanothioacetamide in refluxing ethanolic TEA to give the pyridinethione 2 rather than thiopyrane 4. Compound 2 reacts with α-haloketones to give the s-alkylated derivative