935458-21-2Relevant academic research and scientific papers
Factor Xa inhibitors: S1 binding interactions of a series of N-{(3S)-1-[(1S)-1-methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl} sulfonamides
Chan, Chuen,Borthwick, Alan D.,Brown, David,Burns-Kurtis, Cynthia L.,Campbell, Matthew,Chaudry, Laiq,Chung, Chun-Wa,Convery, Máire A.,Hamblin, J. Nicole,Johnstone, Lisa,Kelly, Henry A.,Kleanthous, Savvas,Patikis, Angela,Patel, Champa,Pateman, Anthony J.,Senger, Stefan,Shah, Gita P.,Toomey, John R.,Watson, Nigel S.,Weston, Helen E.,Whitworth, Caroline,Young, Robert J.,Zhou, Ping
, p. 1546 - 1557 (2008/02/01)
Factor Xa inhibitory activities for a series of N-{(3S)-1-[(1S)-1-methyl-2- morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides with different P1 groups are described. These data provide insight into binding interactions within the S1 primary spe
