935559-76-5Relevant academic research and scientific papers
Competitive cationic pathways and the asymmetric synthesis of aryl-substituted cyclopropanes
Melancon, Bruce J.,Perl, Nicholas R.,Taylor, Richard E.
, p. 1425 - 1428 (2008/02/03)
Equation presented 1,2-Disubstituted cyclopropanes were synthesized in a nonracemic fashion via activation of the corresponding homoallylic alcohols in excellent yields. A series of substituted phenyl rings showed higher enantiospecificity for the cyclization as the electron-withdrawing ability of the group increased. The results offer strong support for the existence of competing cation mechanisms.
