93560-70-4

Upstream product

• 2305-54-6 2-(Anilinomethylen)-2-cyanessigsaeure-ethylester 
• 94-05-3 2-cyano-3-ethoxyacrylic acid ethyl ester 

Downstream Products

• 93560-72-6 2-(Anilinomethylen)-2-cyanessigsaeure-cyanmethylester 
• 93560-71-5 2-(Anilinomethylen)-2-cyanessigsaeure-(2-oxo-2-phenylethylester) 
• 93560-74-8 4-Amino-3-(anilinomethylen)-5-benzoyl-2(3H)-furanon 
• 93560-73-7 2-(Anilinomethylen)-2-cyanessigsaeure-(ethoxycarbonylmethylester) 

Relevant academic research and scientific papers

Synthesis of 2-Acyl-3-aminofurans by Thorpe Cyclization

The substituted β-(acylmethoxy)acrylonitriles 2 and 11, obtainable by O-alkylation of β-cyano ketones with halomethyl ketones or by the reaction of α-hydroxymethyl ketones with β-chloro-α-cyanocinnamonitrile are cyclized in the presence of bases to yield

Quinolone derivatives and their use in a method of controlling an immediate hypersensitivity disease

Compounds of the following formula are described: STR1 in which n is 0, 1 or 2, R1 is C1-4 alkyl, C1-4 alkoxy, C1-4 alkylthio, C1-4 alkylsulphonyl, trifluoromethyl, halo or nitro, and R2 and R3 are each independently hydrogen or C1-4 alkyl, and salts thereof. The compounds are useful in the treatment of immediate hypersensitivity conditions and are prepared by reaction of the appropriate formylquinolone with malonic acid, ylid or phosphonate.